The Buxton Palace Hotel holds a collection of 122 rooms with something for almost every type of guest. There are single, twin, double, triple and family rooms on offer, with twins and doubles available as either standard or premium rooms with seating areas. Typical in-room facilities include satellite TV, coffee/tea facilities, trouser press, iron and board, hairdryer and WiFi Internet access.

There are also four spacious suites, which benefit from a separate lounge area, dining table and desk in addition to standard amenities. Rooms and suites are comfortably furnished, with some attractive Victorian features.